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In low- and middle-income countries, an estimated 4% of childhood morbidity and mortality is due to severe zinc deficiency ( The body responds to insufficient intake with rapid metabolic adaptations aimed at reducing endogenous losses, primarily by lowering zinc-dependent processes, such as growth and immune system functions

In animals with hormonal imbalance, the area of the adrenal gland that usually produces cortisol is incapable of reacting to the ACTH, so that the levels of cortisol remain low

But it does indicate a pattern of service failures that extends beyond isolated incidents