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High levels of this enzyme point to more oxidative stress that needs to be neutralized [42, 43]

Noguchi K, Matsuzaki T, Shiroma N, Ojiri Y, Sakanashi M

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Interestingly, systemically delivered DFP exhibited acute anti-depressant activity in a mouse model of depression without modifying brain and blood iron levels, suggesting an iron-independent mechanism (Uzungil et al., 2022)