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However, given the observational designs, small sample sizes, and lack of control for natural history of placebo effects, these findings require replication in randomized adequately-powered designs

Findings also lead to research gaps due to the limited data on working memory dysfunction, maternal stress impacts, and neurofeedback interventions, alongside inadequate exploration of diet-based treatments

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Products that meet all four are more likely to deliver the modest, real benefits described in the clinical literature