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Targeted ultrasound of the area of palpable concern in the right axilla demonstrates an irregular lymph node with cortical thickening and effacement of the fatty hilum yielding metastatic breast cancer following ultrasound-guided core needle biopsy

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This limitation is particularly relevant when interpreting discrepancies between our findings (e.g., the relatively low ROR for letrozole) and prior literature, as FAERS cannot establish a direct causal relationship between AIs and dermatologic AEs