From a pathophysiological perspective, my first thought is that this could reflect an indirect effect on peripheral nerve sensitivity, possibly related to: rapid shifts in glucoselipid metabolism, changes in nerve conduction due to electrolyte fluctuations, or even a centrally mediated effect, considering GLP-1 receptor expression in the CNS
GLP-1 Receptor Expression and Intestinal Inflammation GLP-1 receptors are expressed on intestinal immune cells, enteric neurons, and epithelial barriers, where they modulate inflammatory responses and bacterial translocation
Hydroxocobalamin - this is a highly bio-available form of B12 and is usually the first choice type of B12 to treat people who have diagnosed B12 deficiencies and/or disorders
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