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Curcumin may also be helpful in recovery after cholecystectomy

Melatonin has been proven to downregulate chondroitin sulfate proteoglycans after spinal cord injury ( In summary, melatonin clearly alters the composition and biomechanical properties of the ECM, thus making the peripheral nerve tissue less stiff and enabling regenerating axons to invade the endoneurium and to reinnervate their targets

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If nausea persists beyond 3-4 weeks on a stable dose, consider reducing to the previous dose level and attempting re-escalation more gradually after 4-6 weeks