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Given that blood cells are continuously exposed to circulating endogenous CTSs, as well as to the therapeutic doses of exogenous CTSs, the aim of our review is to systematize and analyze the data on the impact of diverse CTSs on various blood cells and to elucidate potential molecular mechanisms underlying these effects

I.BowerA.et al (2015)

Intasqui and colleagues showed that overexpression of mucin 5B in normozoospermicmen correlated with increased seminal lipid peroxidation levels, suggesting that this protein contributes to sperm transport alteration in both sexes

Once in the nucleus, NF-B regulates gene expression, activating different genes depending on its composition, with many involved in inflammation, cell growth, and differentiation