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If the patient achieves clinically meaningful weight reduction with obesity medications and if the clinician and patient feel that the medication is helping to avoid weight regain, then a weight reduction plateau should not be considered a point where medication should be discontinued, but rather the medication should be continued for weight reduction maintenance

These medications work by curbing appetite and slowing digestion, naturally leading to lower calorie intake

With this authorization, RJVA-001 becomes the first AAV gene therapy candidate to enter clinical development for type 2 diabetes, said Rajagopalan

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