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In laboratory animals, curcumin has been shown to play a stimulatory role in ovarian functions and prevents the compromise of ovarian functions caused by cyclophosphamide (CPM), ionizing radiation, and ischemia (Alekseyeva et al., 2011

Fraternale A, Paoletti MF, Casabianca A, Oiry J, Clayette P, Vogel JU, Cinatl J Jr, Palamara AT, Sgarbanti R, Garaci E, Millo E, Benatti U, Magnani M

DEEP HYDRATION: Formulated with Hyaluronic Acid, Niacinamide, and Centella Asiatica to hydrate, balance oil, and calm visible redness, leaving skin soft, nourished, and refreshed

Type IV pili interaction with CD147 on endothelial cells has also been demonstrated to induce an increase in sphingosine 1-phosphate receptor 2 (S1PR2) and the activation of the S1P-S1PR2-EGFR axis, leading to bacterial uptake (Fohmann et al., 2023)