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Examples are acetylcholine (produced by Lactobacillus and Bacillus ), gamma-aminobutyric acid (GABA) (produced by Bifidobacterium and Lactobacillus ), serotonin (produced by Bifidobacterium, Lactobacillus , Lactococcus , Enterococcus , Escherichia , Streptococcus ) catecholamine (produced by Escherichia , Lactococcus , Bacillus , Lactobacillus , and Saccharomyces ), and tryptamine (produced by Ruminococcus and Clostridium ) (Onal et al., 2019

Feasibility, acceptability, and safety of faecal microbiota transplantation in the treatment of major depressive disorder: a pilot randomized controlled trial

It is clinically significant

In addition, several clinical trials have shown GLP-1 receptor agonists have demonstrated the capacity to reduce cardiovascular events and mitigate kidney disease