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Discussion In the present study, we found that GLP-1R protein levels decreased significantly in a knee OA rat model induced by monoiodoacetate, which was accompanied by the downregulation of the PKA/CREB pathway and upregulation of the inflammation-related proteins TNF-, IL-6 and IL-1

After stopping a GLP-1 medication, its effects on gut motility gradually diminish as the drug leaves the system

For example, gut microbiota can affect the synthesis and release of neurotransmitters by producing short-chain fatty acids (SCFAs) such as acetic acid, propionic acid, and butyric acid

KhamseekaewJKumfuSWongjaikamSKerdphooSJaiwongkamTSrichairatanakoolSet alEffects of iron overload, an iron chelator and a T-type calcium channel blocker on cardiac mitochondrial biogenesis and mitochondrial dynamics in thalassemic mice