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10.5214/ans.0972.7531.220406 46 NagaokaT.TakashiS.FumihikoM.EiichiS.AkitoshiY

In isolated sinus nodes, GLP-1 shortens action potential cycle length and shifts the site of earliest activation independently of HCN channel conduction To further investigate the electrophysiological effect of GLP-1 on the sinus node, isolated porcine sinus nodes (see Supplementary material online, Figure S6A ) were exposed to continuous superfusion with GLP-1, ivabradine, or ivabradine + GLP-1

In the cellular component category, cell and membrane were dominant