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Follistatin Gene Therapy Research in Humans Phase 1/2a clinical trial data for AAV1-FS344 in Becker muscular dystrophy patients demonstrated a statistically significant average 11.5% improvement in six-minute walk test performance at 6 months (p = 0.02), with the degree of pre-existing muscle fibrosis at baseline identified as the strongest predictor of treatment response

104,105 Future trials in patients infected with mutated SARS-CoV-2 strains may help to confirm or refute the possibility of a treatment benefit with N-acetylcysteine

Although this review provides a comprehensive analysis of the existing literature on the topic, there are several limitations that must be acknowledged

consensus statement from the July 1, 2022 Lugano Workshop on recurrent implantation failure