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Some dysplastic nevi have been found to exhibit unique gene expression patterns, mutation or altered expression of p16 and p53, and increased microsatellite instability [37]

Microglia populate the CNS during early embryogenesis and primarily function in the phagocytosis of cellular debris, synaptic pruning during neurodevelopment and maturation, and the release of cytokines and growth factors that influence neuronal survival and plasticity (Ginhoux and Prinz, 2015)