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In ovarian cancer multicellular spheroids, platelet releasate promotes growth, expansion of ALDH+ and CD133+ cancer stem cells, and protection against the cytotoxic effects of cisplatin, carboplatin and paclitaxel

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Besides, for the primary biomarker-outcome relationship (IGF-1 and CRC), which constituted the main focus of our synthesis and included the largest number of studies, we re-fitted the meta-analysis before and after removing high-influence studies