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GLP-1 therapy targets appetite and fat loss, while hormone optimization supports muscle preservation, metabolic balance, and long-term sustainability

Animal studies suggest these patches may help reduce weight, likely because direct delivery into the skin can improve absorption compared with oral supplements

GLP-1 expression was significantly decreased on day 5 (0.56 0.18) and day 9 (0.60 0.14) (Fig

*Correspondence: Marco Falasca [email protected] This article was submitted to Cellular Endocrinology, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers