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It is well known that TGF- prevents the sensitized T cells migration into the CNS, and protects against EAE and MS, while IL-12 may play a major role in EAE development through the induction of both Th1 and Th17 cells differentiation, and both may play a complementary role in the EAE disease pathogenesis (Jafarzadeh and Nemati, 2018)

Lifestyle changes are crucial for long-term weight management

Its impact on inactivation of mitochondrial proteins depends on the level of generation in mitochondria

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