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The current KDIGO guidelines do not recommend SGLT2i for people in more advanced stages of CKD (eGFR 300 mg/g) and reduced progression of UACR in people with macroalbuminuria when compared with placebo
Treatment: Combination of minoxidil 5%, spironolactone (anti-androgen), PRP treatments, nutritional optimization, and low-level laser therapy
This underscores the need for gender-specific approaches in clinical practice, optimizing the therapeutic efficacy of GLP-1 analogs based on patient characteristics and symptomatology
8-13 For a detailed discussion of cardiovascular outcome trials (CVOTs) completed with agents from the GLP-1 RA class, please refer to the companion lesson titled: What do we Currently Know about the Cardiovascular Benefits of GLP-1 RAs
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