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Yonsei Medical Journal, 47 (5), 614625

(1) Review labels to avoid excess added sugars (1) and sugar alcohols which can cause GI distress (17), and discuss long-term use with your healthcare team

Experimental studies in humans have shown that sleep disturbances such as circadian rhythm misalignment (44) and sleep deprivation (45) lead to gut microbiota dysbiosis, with a decrease in microbial diversity, an increase in Firmicutes/Bacteroidetes ratio, and a decrease in short-chain fatty acid production