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A tirzepatida aumenta a sensibilidade das clulas glicose, estimulando a secreo de insulina tanto na primeira quanto na segunda fase, alm de reduzir os nveis de glucagon, ambos de maneira dependente da glicose
Nausea affected up to about 29 percent of participants Diarrhea up to about 23 percent Vomiting up to about 13 percent in some studies Reports of sleep disturbance or insomnia were not prominent in the trial safety tables for Zepbound
doi: 10.1016/j.hbpd.2022.08.006 55 ZengCHuaSZhouJZengTChenJSuLet al
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