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Furthermore, NO produced by iNOS in M1 macrophages can exacerbate lipid peroxidation and ferroptosis in co-cultured CRC cells (123)

Planta 236:765779 Pignocchi C, Kiddle G, Hernndez I, Foster SJ, Asensi A, Taybi T, Barnes J, Foyer CH (2006) Ascorbate oxidase-dependent changes in the redox state of the apoplast modulate gene transcript accumulation leading to modified hormone signaling and orchestration of defense processes in tobacco