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Remarkably, in a trial using high-dose thiamine for fatigue related to inflammatory bowel disease (IBD), the relative abundances of Faecalibacterium prausnitzii , a member of the Ruminococcacea family, and Roseburia hominis , a member of the Lachnospiraceae family, inversely correlate with fatigue severity both pre- and post-treatment with thiamine (62)

Published literature has examined BPC-157 across a range of cell-culture and animal research models relating to cell-migration and angiogenesis-related signaling biology

A systematic appraisal of mechanisms, applications, and strategies to overcome current limitations is therefore essential to advance clinical translation