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With portosystemic encephalopathy , it is now recognized that very mild impairment may affect social skills and emotional behavior, and evaluation of driving skills may be a practical index to diagnose what is termed minimal hepatic encephalopathy (MHE)

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Patients with low levels may experience: Chronic fatigue Weakness Headaches Dizziness Problems sleeping Frequent illnesses Dermatitis Difficulty concentrating Painful joints Mood instability or depression There are also many chronic health conditions which are associated with low glutathione levels

Depress Anxiety 26 : 796805