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Neurosci Biobehav Rev 37:28872899 Liu D, Li S, Gong L, Yang Y, Han Y, Xie M, Zhang C (2019) Suppression of microRNA-141 suppressed p53 to protect against neural apoptosis in epilepsy by SIRT1 expression
Many women experience mood swings, anxiety, and even depression due to hormonal fluctuations
In the absence of enough iron in cells, an iron starvation response begins, increasing iron availability by increasing TFCR1 and decreasing the levels of FTH and ferroportin (FPN) ( 2.1.2 Iron homeostasis Under normal circumstances, intracellular iron maintains a subtle balance through the iron transport system ( Iron homeostasis dysregulation is involved in ferroptosis, and multiple iron metabolism regulatory factors work together to maintain iron homeostasis ( 2+ levels and lipid peroxidation, inhibiting ferroptosis ( 2.2 Ferroptosis and lipid metabolism The conversion of lipids into membrane phospholipids and the occurrence of peroxidation are necessary conditions for ferroptosis ( Acyl-CoA synthetase long chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 are key enzymes involved in the process of lipid peroxidation (56)
