doi: 10.1016/j.ibmb.2026.104563 Wu, Jianxin, Gao, Ling, Villanueva, Jeanette, Doyle, Aoife, Dutta, Sanjay, Joshi, Yashutosh, MacLean, Campbell, Kesteven, Scott, King, Glenn, Palpant, Nathan, Feneley, Michael, Iismaa, Siiri, Graham, Robert and Macdonald, Peter (2026)
Bariatric surgery is a treatment option for obesity that can lead to liver steatosis and fibrosis regression
Most reported side effects of these peptides in studied doses are mild (injection-site irritation, transient sleep or vivid dreams, headaches), but longterm, largescale human safety dataespecially for longevity useremain limited
An enzyme called tyrosinase is needed to create melanin (the pigment that causes the brown spots) and while several other skin lightening agents work to inhibit the synthesis of tyrosinase itself (like vitamin C or licorice), arbutin lets tyrosinase be and rather hinders the melanin-forming activity of the enzyme