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Regular follow-ups, either in-person or via telehealth, allow for real-time monitoring and dose adjustments

Normal adjustment symptoms These are expected and typically manageable: loose stools 1 to 3 times daily during dose escalation, mild abdominal cramping before bowel movements, increased urgency (needing to go sooner than usual), softer stool consistency without other alarming features, symptoms that correlate with recent dose increases, and gradual improvement over 2 to 4 weeks at a stable dose