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Small human studies of first-trimester inadvertent exposure report no elevated risk of major congenital malformations or pregnancy loss, but evidence is preliminary and observational

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Interestingly, the combined application of GLP-1 and GIP resulted in a greater decrease in bone resorption than was seen with these hormones alone ( Recently, in light of the advent of DPP-IV inhibitors, which serve as enzyme inhibitors for insulin hormone degradation and are being used as therapeutic interventions for individuals with diabetes, there has been a mounting curiosity surrounding the impact of these pharmaceutical agents on skeletal well-being (Meier et al., 2016)