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Because peptide-based supplements may affect individuals differently, it is important to follow label directions carefully and discontinue use if unusual reactions occur.

"Patients are getting what purport to be these substances, or are using drugs that are made with research-grade active ingredients, and I almost expect any day now there's going to be some serious patient adverse event or a series of patients who are made ill or worse by taking batches of these drugs that were not made to FDA standards or with active ingredients that are not made to FDA standards," Brunner said

Researchers suggest that the GHK sequence may occur endogenously, specifically being released by cells, including fibroblasts, macrophages, and lymphocytes, during damage, as a result of collagen breakdown

2 Niacinamide (Vitamin B3): Niacinamide helps to strengthen the skin barrier, reduce inflammation, and improve elasticity