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If fatigue , medication tolerance , or persistent GI distress has made pharmaceutical GLP-1 drugs unworkable, a probiotic approach offers a fundamentally different mechanism with a much milder side effect profile

Gibbons et al., studied the effect of oral semaglutide in 15 subjects with type 2 diabetes and reduction on appetite and craving, demonstrating not just the reduction in calorie intake, but also lowering the palatability and preference for sweet and high fat food (177)

Any leftover glucose is then packaged into glycogen molecules so it can be stored in the liver for later

This review has significant implications for the management of T2D, making it a compelling read for healthcare professionals, researchers, and clinicians