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It essentially acts on the same receptors as Sermorelin (GHRH receptors in the pituitary) but with a crucial difference: the DAC version of CJC-1295 binds to albumin , giving it an extended half-life of about 1 week

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FIGURE 7 Previous studies have shown that deferoxamine (DFO) inhibits the growth of esophageal squamous cell carcinoma (ESCC) cells by activating the ERK pathway in a ROS-dependent manner (Supplementary Figure S3E), and treatment with 800 M CGA led to a significant increase in ROS accumulation in hepatocytes (Figures 7F,G)