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Acknowledgements This work benefited from access to CERMAX, ITQB-NOVA, Oeiras, Portugal with equipment funded by FCT, project AAC 01/SAICT/2016

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After the DLT intervention, the Fe 2+ levels in liver tissue of mice were significantly reduced, and the protein and mRNA expression levels of GPx4 and ferritin heavy chain (FTH1) were apparently elevated, and the cytoplasm was brownish yellow and dark in color (91)