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To obtain the best glycemic control, Rybelsus can be administered either on its own or in conjunction with other antidiabetic drugs

Samuel Lin, an associate professor of surgery at Harvard Medical School and a Boston-based plastic surgeon, tells TODAY.com

Less common, but more serious side effects can include: Pancreatitis Hypoglycemia Allergic reactions (rash, facial swelling, trouble breathing, fainting, rapid heartbeat) Kidney failure Gastrointestinal issues Vision changes Gallbladder issues (stomach pain, fever, jaundice, discolored stool) Differences Mechanism of Action: Semaglutide predominantly functions as a GLP-1 agonist, targeting specific pathways to facilitate its effects

With semaglutide, my energy remained consistent throughout the day