tirzepatide hfpef trial Effects of on the Clinical Trajectory of Patients With Heart Failure, Preserved Ejection Fraction, and Obesity STEP-HFpEF Trial

Renal events include elevations in serum creatinine, oliguria, interstitial nephritis, and, rarely, nephrotic syndrome

Common side effects at diabetes doses can include: Nausea Diarrhea Decreased appetite Vomiting Typical Side Effects Seen with Higher Weight Loss Doses As you increase to a high dose of tirzepatide for weight loss, you may notice that some gastrointestinal side effects reappear or intensify

Regular monitoring of kidney function, blood glucose, and hydration status is essential

Follow-up periods range from months to years, and the time-dependent nature of some risks means shorter studies may miss problems that appear later