The short answer is an unequivocal, absolute yes
[8] Further signs that may be seen on physical examination are most commonly a diffusely enlarged (usually symmetric), nontender thyroid, lid lag, excessive lacrimation due to eye exposure from Graves' ophthalmopathy, arrhythmias of the heart, such as sinus tachycardia, atrial fibrillation, and premature ventricular contractions, and hypertension
In AD, mitochondrial transport is compromised: dynein/kinesin dysfunction, caused by A oligomers inhibiting motor proteins, prevents mitochondria from moving along axons and dendrites
Kan HP, Wu FL, Bin Guo W et al (2013) Null genotypes of GSTM1 and GSTT1 contribute to male factor infertility risk: a meta-analysis