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Diabetologia 60(10):20662075

In addition, the brain regions involved in mediating the effects of GLP-1 on gastric emptying and satiety differ, given that the threshold dose of GLP-1 required to inhibit gastric emptying is 3,000 to 10,000 times lower than the reported threshold doses necessary to suppress feeding behavior (161)

This might affect how well other medications work

Importantly, many patients find these taste changes helpful rather than problematic, as they facilitate adherence to reduced-calorie diets and support weight management goals