Kasagga A, Assefa A, Amin MN, et al
If confirmed, treatment with semaglutide should not be restarted Gallbladder problems : Rapid weight loss can increase the risk of gallstones, which may cause right upper abdominal pain, fever, or yellowing of the skin/eyes (jaundice) Diabetic retinopathy complications : Patients with existing eye disease should be monitored closely, especially during periods of rapid improvement in blood glucose control [22] [23] Acute kidney injury : Usually associated with severe dehydration from gastrointestinal side effects Allergic reactions, though rare, can occur and may present as rash, itching, or difficulty breathing
It has been proposed that NAD(P)H:quinone oxidoreductase 1 (NQO1) acts as a redox-sensitive switch to regulate the response of cells to changes in the redox environment (Ross and Siegel, 2017)
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