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How Tirzepatide Works: Weekly subcutaneous injection Dual receptor activation (GLP-1 + GIP) Enhanced metabolic benefits Greater average weight loss in clinical studies Side-by-Side Comparison: Semaglutide vs Tirzepatide Effectiveness Semaglutide: Average 12-15% body weight loss Tirzepatide: Average 15-20% body weight loss Both medications show significant results, but individual responses vary