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Int J Mol Sci 22(13):7121 Neves D, Salazar IL, Almeida RD, Silva RM (2023) Molecular mechanisms of ischemia and glutamate excitotoxicity

Among those over the age of 60, about 2% have the condition

As GPX4 activity is heavily dependent on GSH availability, upregulation of SLC7A11 enhances GPX4 function and prevents ferroptosis

Although mitochondrial respiration was noted as unchanged in resting and stimulated CD4+ and CD8+ T cells, CD8+ T cells were found to have a reduction in proton leak, ATP synthesis, and mitochondrial membrane potential (254)