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Abbreviations ACSL1: Acyl-CoA synthetase long-chain family member 1 AMPK: Adenosine monophosphate-activated protein kinase ATF: Activating transcription factor ATG16L1: Autophagy-related 16-like 1 AP-1: Activator protein-1 BBR: Berberine CARD9: Caspase recruitment domain-containing protein 9 CD: Crohns disease CHOP: C/EBP homologous protein CLEC7A: C-type lectin domain family 7 member A CMA: Chaperone-mediated autophagy CSNK2B: Casein kinase 2 beta DAPK: Death-associated protein kinase eIF2: Eukaryotic initiation factor 2 alpha ER: Endoplasmic reticulum ERO1: ER oxidoreductin 1 alpha FMT: Fecal microbiota transplantation GPX4: Glutathione peroxidase 4 GSK-3: Glycogen synthase kinase 3 beta HSP5A: Heat shock protein family A IL: Interleukin IBD : Inflammatory bowel disease IECs : Intestinal epithelial cells IRGM : Immunity-related GTPase M MO : Magnolia officinalis cortex mTORC1 : Mammalian target protein 1 of rapamycin NOD2 : Nucleotide-binding oligomerization domain 2 PPAR : Peroxisome proliferator-activated receptor S1P : Site-1 protease SCFAs : Short-chain fatty acids TLR : Toll-like receptor TNF : Tumor necrosis factor TRAF2 : Receptor-associated factor 2 UC : Ulcerative colitis UPR : Unfolded protein response Xbp1 : X-box binding protein 1 References Kastl AJ Jr, Terry NA, Wu GD, Albenberg LG