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As B12 deficiency results in the accumulation of these compounds, levels will appear elevated

Specifically, KPV is a fragment of alpha-melanocyte-stimulating hormone (-MSH), a larger peptide with anti-inflammatory, antimicrobial, and fever-reducing properties.1 Even more specifically, the fragment in question is the C-terminal region of -MSH, which is particularly good at neutralizing pathogens.2 While many therapeutic peptides are taken exclusively by needle, KPV stands apart in that it can also be administered as an oral capsule or chewable tablet

Marked reduction of cerebellar deficits in upper limbs following transcranial cerebello-cerebral DC stimulation: tremor reduction and re-programming of the timing of antagonist commands

This explains why high levels of oxidative stress is implicated not just in neurodegenerative conditions but cardiovascular diseases as well