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Other at-risk populations include individuals on chronic steroids, which cause muscle wasting, patients unable to engage in strength and resistance training, or patients with muscle-wasting conditions like chronic kidney disease. McGowan also noted that even healthy individuals should expect some muscle loss

Professional antigen-presenting cells like macrophages release substantial amounts of cysteine, raising intracellular glutathione levels in activated T cells and supporting optimal immune function

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Commonly reported side effects include: Nausea, vomiting, and diarrhoea particularly during dose escalation Constipation and abdominal discomfort Decreased appetite and early satiety Injection site reactions (mild and transient) Fatigue, especially in the initial weeks of treatment These gastrointestinal effects are consistent with the GLP-1 mechanism and are generally dose-dependent and transient