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10.1017/S0029665199000580 38 SelhubJ.MorrisM

reported that TMAO triggers dose-dependent unfolded protein response in aortic valve interstitial cells, increasing PERK/IRE-1 phosphorylation and ATF-4/XBP-1 s expression (Xiong et al., 2024)

The iAUC for tirzepatide was calculated from minutes 4280, using the value at minute 42 as the baseline for each sample, and is expressed as a function of time (ng/(islet min) min)