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Important safety considerations include the boxed warning for thyroid C-cell tumors (contraindicated in patients with personal/family history of MTC or MEN2), and risks of pancreatitis, gallbladder problems, diabetic retinopathy complications, and acute kidney injury from dehydration

Early studies and observational reports suggest GLP-1 medicines may reduce drinking or cravings in some groups

Although moderately effective in the treatment of cystic fibrosis, hypertonic saline aerosols can hydrate healthy airways for short periods of time, typically around 30 min

It was found to aid with weight loss too, and so the product Wegovy was licensed in the UK, which is semaglutide for weight loss