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also confirmed in an ovariectomized rat osteoporosis model that IQ-Lips significantly improved bone microstructure compared with free IQ (increased bone volume fraction, trabecular thickness, trabecular number, bone mineral density
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PRL by increasing circulating adiponectin shows beneficiary effect on metabolism function, and these actions depends on circulating PRL levels kept at a relatively high concentration, but within a physiological range (within 7 and 100 ng/mL), defined as homeostatic functionally increased transient prolactinemia by Macotela ( via the transcriptional activation of CEBP alpha and PPAR gamma (95)
And the introduction of oral GLP-1 formulations, including the FDA approval of oral semaglutide for chronic weight management, expanded options beyond injectable formats.
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