diabetic retinopathy glp 1 Are GLP-1 receptor agonists and foes or friends? GLP-1s Don’t Cause Diabetic Retinopathy

As noted by others ( Of note, the finding of a markedly greater benefit on HF of efpeglenatide amongst trial participants using SGLT2 inhibitors at enrolment in the AMPLITUDE-O CVOT highlights another important point ( Another drug class widely used to treat type 2 diabetes is inhibitors of the enzyme dipeptidyl peptidase-4 (DPP4), which mediates enzymatic breakdown of GLP-1

While all of these potential benefits are exciting, experts said they need much more study, and even then, whether they might ever be utilized as a treatment for schizophrenia, for example, would depend on a number of factors: how much and how consistently they work, as well as how they compare to treatments that are already available

Diabetes Care (2020) 43(5):108593

Lastly, EX-4 enhances cognitive function in APPxPS1-Ki AD mice by improving short- and long-term memory and increasing brain lactate levels, indicating a shift toward anaerobic glycolysis