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This means more fat burned for fuel instead of being stored

Understanding the complete path helps manage expectations during the early phase when weight loss is minimal and the focus is entirely on adaptation

Activation of central GLP-1 receptors enhances neuronal insulin signaling, improves glucose uptake, and supports mitochondrial energy production

In addition, after ischemia-reperfusion injury, the expression of proinflammatory cytokines, NF- B and ICAM-1, as well as macrophage infiltration in the kidney was significantly decreased by exendin-4 (10 g/kg) or sitagliptin (600 mg/kg) treatment [109]