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Researchers found that HS patients who had received GLP-1 receptor agonists experienced significantly lower rates of mortality, cardiovascular complications, and several inflammation-related conditions compared with similar patients who had not used these therapies

[Abstract] Redox Biol

Thus, considering evidence documenting the existence of various GLP-1-producing subpopulations of alpha-cells in the adult pancreas, these results would indicate that a range of alpha-cell maturity exists within the adult pancreas

Occasionally, surgery is necessary if a prolactinoma does not respond to medication or if the patient cannot tolerate the medication