They received retatrutide once weekly for an additional 24 weeks, including a blinded escalation to maximum tolerated dose of 9 mg or 12 mg
Some have substantial excess body fat and co-morbidities that they're trying to manage through exercise, and may actually be great candidates for GLP-1 use
The relationship between GLP-1 receptor agonists and thyroid function is complex and not fully understood, which has prompted further investigation into the safety and efficacy of semaglutide in patients with thyroid disorders
When to contact your healthcare provider Contact your healthcare provider right away if you have: Thoughts of suicide or self-harm Severe rash, skin peeling, or blisters Yellowing of your skin or eyes Dark urine or upper stomach pain Confusion, rapid heart rate, or severe muscle stiffness Unusual or heavy bleeding Signs of a severe allergic reaction, like swelling of the face, lips, or throat, or trouble breathing References Cymbalta (duloxetine) prescribing information
