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Inhibition of cysteine-glutamate transporter protein system (e.g., Erastin) will deplete intracellular GSH, eventually resulting in the inactivation of GPx4 and the accumulation of lipid peroxidation, which can induce cell ferroptosis to a certain extent [75]

Preclinical work has reported a distinct selectivity profile, with growth hormone stimulation observed at concentrations that did not trigger ACTH or cortisol secretion, making it a useful tool for isolating growth hormone-specific signalling without activation of the hypothalamic-pituitary-adrenal axis

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Taylor & Francis, Boca Raton, pp 177184 Hovorkov P, Laloukov K, Skivanov E (2018) Determination of in vitro antibacterial activity of plant oils containing medium-chain fatty acids against Gram-positive pathogenic and gut commensal bacteria