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BelaunzaranZamudio at the National Institute of Allergy and Infectious Diseases

GLP-1 (glucagon-like peptide-1) medications, often prescribed for managing diabetes or aiding weight loss, can sometimes impact nutrient absorption, leaving users with vitamin deficiencies they might not even realize they have

In the simulation of F347, the ligand adopts the same orientation as in the crystal structure, whereas the orientation of the ligand in the simulation of C347 is varied during the simulation process (the trifluoromethyl-pyrazole group in particular)